Synthetic human embryos obtained from stem cells? Artificial monkey embryo research leads the way

Synthetic human embryos obtained from stem cells?  Artificial monkey embryo research leads the way

IIn January 2017, I met Jiankui He, the now-infamous Chinese scientist who would go on to create the world’s first genome-edited babies. This occurred during a meeting in Berkeley, California hosted by Jennifer Doudna who, along with Emmanuelle Charpentier, was awarded the 2020 Nobel Prize in Chemistry for her work on CRISPR genome-editing technology. In … Read more

University of Toronto researchers present scGPT: a basic model for single cell biology based on a generative transformer pre-trained in a repository of more than 33 million cells

University of Toronto researchers present scGPT: a basic model for single cell biology based on a generative transformer pre-trained in a repository of more than 33 million cells

https://www.biorxiv.org/content/biorxiv/early/2023/07/02/2023.04.30.538439.full.pdf Natural language processing and computer vision are just examples of the fields where pre-trained generative models have been incredibly successful. In particular, a viable strategy for building foundation models is to combine various large-scale datasets with pre-trained transformers. The study investigates the feasibility of basic models for further research in cell biology and genetics … Read more

Antisense therapy restores fragile X protein production in human cells

Joel D. Richter, PhD, and Sneha Shah, PhD

image: Joel D. Richter, PhD, and Sneha Shah, PhD visualization Moreover Credit: UMass Chan Medical School An antisense therapy developed by Joel D. Richter, PhD, Sneha Shah, PhD, and Jonathan K. Watts, PhD, at UMass Chan Medical School and Elizabeth Berry-Kravis, MD, PhD, at RUSH University Medical Center, restores production of the FMRP protein in … Read more